Subscribe via RSS Feed

Method for detecting TAG-72 using CC92 and CC49 monoclonal antibodies and use thereof for cancer diagnosis, prognosis and monitoring

A prototype cancer immunodiagnostic kit was developed which detects the presence of the pancarcinomic tumor antigen TAG-72 in serum. This ELISA sandwich method makes use of the monoclonal antibodies against TAG-72, namely: CC92 as capture antibody and CC49 as detecting antibody. When TAG-72 levels are measured in parallel with CEA levels (standard cancer diagnostic), monitoring and prognosis of cancer patients can be improved.

Patent Application Status: Philippine Patent Pending

Date of Filing: 12 July 2004
Application No.: 1-2004-00285

About the Inventor:

  • Gisela P. Concepcion

    Current Position: Associate Professor, Marine Science Institute, UP Diliman Q.C.
    Research Interests: Marine Natural Products, Biochemistry, Development of Bioscreening Methods

In vivo method for selecting antibodies, their derivatives and antibody-mediated therapies against breast cancer

A mouse tumor model was developed that allows the preliminary testing of candidate therapeutic antibodies and antibody conjugates targeted to the human pancarcinomic tumor antigen TAG-72. A mouse tumor antigen, expressed on the surface of mouse mammary tumors growing in mice, is detected by the TAG-72 monoclonal antibody CC49 by immunohistochemistry. The mammary tumor in mice regresses when intravenously injected with CC49 or a CC49-drug conjugate.

About the Inventor:

  • Gisela P. Concepcion

    Current Position: Associate Professor, Marine Science Institute, UP Diliman Q.C.
    Research Interests: Marine Natural Products, Biochemistry, Development of Bioscreening Methods

Cyclic hexapeptides, process and use thereof

Two novel cyclic hexapeptides, microcionamides A and B, which are geometric isomers, were isolated from a sponge collected in the Philippines. These compounds exhibit significant cytotoxicity and induce apoptosis (programmed cell death in human cancer cell lines.

About the Inventor:

  • Gisela P. Concepcion

    Current Position: Associate Professor, Marine Science Institute, UP Diliman Q.C.
    Research Interests: Marine Natural Products, Biochemistry, Development of Bioscreening Methods

Salivary IgA E. histolytica Detection Kit

Dr. Rivera and his team developed a fast, accurate and convenient detection kit for Entamoeba histolytica, the pathogen that causes amebiasis. The Salivary IgA E. histolytica detection kit is more accurate and less time-consuming than traditional methods of identifying E. histolytica such as microscopy. The kit is self-contained and results can be read without the use of specialized instruments. The kit uses salivary samples, which are more convenient to obtain from patients, as opposed to stool samples which are used by traditional E. histolytica detection methods.

About the Inventor:

  • Windell Rivera

Current position: Associate Professor Institute of Biology, College of Science, UP Diliman Q.C.
Research Interests: Molecular Biology and Immunology, Medical Biotechnology, and Molecular Diagnostics and Epidemiology

  • Angeline Odelia Concepcion
  • Alexander Edward Dy

UP in Alibata Characters & Device

Description of the Mark:

The mark consists of a rectangular-shaped band of cloth tapered at the top and flowing at the bottom.  In the middle of the device is a column with a design of a flower followed by the Alibata character for “U” and the Alibata character for “P”.  On both sides of the column containing the letters and flowers is a column of diamond shaped figures bordered by a zigzag line and straight line thereafter.  On the left side of the left diamond column is a wide column followed by a narrow column and a wide column thereafter.  On the right side of the right diamond column is a wide column followed by a narrow column and a wide column thereafter.

Manner of Using the Mark:

By means of displaying in academic costumes, signages at its offices, in business cards, stationeries, magazines, contracts, brochures, announcements, pamphlets, displays and other materials published or used in connection with the services, or in any manner customary to the trade.

Registration No.: 4-2002-0010939
Date of Registration: 01 October 2005
Date of Issuance of Certificate of Registration: 26 April 2006

About the Creators:

  • Virginia D. Monje is a Professor at the National Institute of Molecular Biology and Biotechnology of the College of Science.
  • Rogelio L. Juliano Jr. (deceased) is a former Associate Professor at the Department of Speech Communications and Theater Arts of the College of Arts and Letters.
  • Abraham P. Sakili is an Associate Professor at the Department of Art Studies of the College of Arts and Letters.
  • Antoinette B. Hernandez is an Associate Professor at the Department of Speech Communications and Theater Arts of the College of Arts and Letters.
  • Consuelo J. Paz is a retired Professor at the College of Social Sciences and Philosophy.
  • Carmen G. Diaz de Ventanilla is a retired Professor at the University of the Philippines.

Seamoy & Device

Description of the Mark:

Colored leaf borders are present. The name “Seamoy” is on the upper left part. Dominant color is blue green, shadowed. Text format is wavy. Scent variant is indicated below “Seamoy”. The texts “Air-freshener gel” and “Product of Marine Science Institute, UP Diliman” are present.

Date of filing: 30 May 2007

Status:

  • Registered as of June 8, 2009.

About the Creator:

Marco Nemesio E. Montaño is a Professor at the Marine Science Institute of the College of Science. His main research interests are on marine natural products, algal polysaccharides, and marine pollution chemistry.

Euginthol & Device

Description of the Mark:

“Euginthol” text is mainly colored green, fading from dark green to light green downward. The text is bordered by light and dark blue lines. A yellow green colored candy and seaweed serve as background.

Date of filing: 30 May 2007

Status:

  • Registered as of October 27, 2008.

About the Creator:

Marco Nemesio E. Montaño is a Professor at the Marine Science Institute of the College of Science. His main research interests are on marine natural products, algal polysaccharides, and marine pollution chemistry.

UP Sablay

The UP Sablay is the official academic costume of the University of the Philippines. The official colors of the University, maroon and green, were used in the sablay. Yellow gold, which stands for the high standards of values and excellence, was also used. The colors, based on the Panthone ProSim color chart, are Panthone 195 CVP (maroon), Panthone 349 CVP (green), and Panthone 138 CVP (yellow gold).The indigenous letters Alibata for U and Alibata for P, originating from the indigenous alphabet called baybayin or katitikan, are equivalent to the Roman letters “U” and “P”, respectively. The curvilinear design called ukkil or ukit, which resembles a sprouting plant, signifies life. The geometric designs (in zigzag and diamond patterns) are common design elements gracing the attires and functional objects of indigenous peoples from Batanes to Tawi-tawi. Arranged continuously and rhythmically, these geometric designs highlight the diverse cultural communities in the Philippines and the University’s pursuit of knowledge, cultural enrichment, and scientific advancement.

Date of Registration: 13 September 2002
Date of Issuance of Certificate of Copyright Registration and Deposit: 23 September 2002

About the Creators:

  • Virginia D. Monje is a Professor at the National Institute of Molecular Biology and Biotechnology of the College of Science.
  • Rogelio L. Juliano Jr. (deceased) is a former Associate Professor at the Department of Speech Communications and Theater Arts of the College of Arts and Letters.
  • Abraham P. Sakili is an Associate Professor at the Department of Art Studies of the College of Arts and Letters.
  • Antoinette B. Hernandez is an Associate Professor at the Department of Speech Communications and Theater Arts of the College of Arts and Letters.
  • Consuelo J. Paz is a retired Professor at the College of Social Sciences and Philosophy.
  • Carmen G. Diaz de Ventanilla is a retired Professor at the University of the Philippines.

Introduction to Semiconductor Devices & Circuits (Textbook)

Introduction to Semiconductor Devices & Circuits is the textbook on introductory electronics course that addresses not only the circuit analysis and design of electronic devices, but also their construction and physics which will be helpful to provide adequate preparation for those students who will be specializing in microelectronics.

Date of Registration: 29 August 2007
Date of Issuance of Certificate of Copyright Registration and Deposit: 05 September 2007
Registration No.: A2007-1906

About the Author:

Dr. Luis G. Sison is a faculty member of the Department of Electrical and Electronics Engineering. He is also the present Vice Chancellor for Research and Development

Data Structures (Textbook)

Data Structures is the textbook on data structure course for sophomore Computer Science students.

Date of Registration:  30 March 2007
Date of Issuance of Certificate of Copyright Registration and Deposit: 19 April 2007
Registration No.: A2007-726

About the Author:

Evangel P. Quiwa
is a faculty member of the Department of Computer Science.  He is also the present College Secretary of the UP College of Engineering.

Page 33 of 34« First...1020...3031323334